Albert Einstein Cancer Center

The Charles E. Rogler laboratory is studying the roles of miRNA in hepatocarcinogenesis and hepatitis B virus replication. MiRNAs that are up or down regulated in hepatocellular carcinoma have been identified and projects are planned to investigate the targets of those miRNAs and their function in tumorigenesis. Also, cellular miRNAs that regulate HBV replication have been identified and the mechanism of their inhibition of replication is a project to be carried out.