Albert Einstein College of Medicine
 

  Training Program in Cellular and Molecular
Biology and Genetics

 

Supported by National Institutes of Health Grant
5 T32 GM07128

 

Research Areas
glycobiology
Signal Transduction
Transgenic mice
Cancer
Cell Biology
Biochemistry
Microbioloy and Immunology
Genetics
Development
The 63 faculty who participate as trainers for the program in cellular and molecular biology and genetics have interests in a broadly defined core of modern molecular biology/ biotechnology. Follow the links to areas of interest to identify faculty participating in this program and to browse their home pages for research details.

Note that faculty interests don't necessarily match their department affiliation. There are no boundaries at Einstein!. Choose an area of interest or browse.



 
   
Glycobiology Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics

 

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Signal Transduction Jonathan M. Backer
Signaling by phosphoinositol kinases.

Chi-Wing Chow
Molecular Mechanisms that control cell growth and development

Luciano D'Adamio
Regulation of programmed cell death by presenilins and Amyloid Precursor Protein.

Todd Evans
Regulation of hematopoiesis and cardiogenesis by embryonic signaling pathways and GATA transcription factors.

Rachel Hazan
Breast Cancer, metastasis, cell adhesion molecules growth factor receptors.

Richard N. Kitsis
Cell-cycle regulation; terminal differentiation apoptosis.

Fernando Macian
Molecular basis of immune tolerance.

Tamar Michaeli
Signal transduction pathways regulating cellular proliferation differentiation and physiology.

Charles Rubin
Signaling via protein kinase A and AKAPs

E. Richard Stanley
Growth factor and signal transduction in the regulation of cell proliferation and development.

Jonathan Warner
Gene analysis of ribosome synthesis in yeast; regulation of MRNA splicing.

Liang Zhu
Relinoblastoma protein family of growth suppressors and cell-cycle control.

Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics
 

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Mouse Models
of Disease
Maureen J. Charron
Glucose transporters biology, Glucagons receptor, Hormone action, Cellular proliferation.

Winfried Edelmann
Mouse models for colorectal cancers, tumor suppressor genes and DNA repair genes

Thomas Graf
Stem cell plasticity; hematopoietic stem-cell biology: leukemo-genesis and transcription factors.

Richard N. Kitsis
Cell-cycle regulation; terminal differentiation apoptosis.

Jeffrey Pollard
Estrogen and progesterone regulation of uterine and mammary gland cell proliferation and differentiation, placental immunity.

E. Richard Stanley
Growth factor and signal transduction in the regulation of cell proliferation and development.

Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics
 

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Cancer Nancy Carrasco
Molecular characterization and medical relevance of the iodide transporter (NIS).

Geoffrey Childs
Functional genomics, mechanisms of lineage specification and tumor classification using microarrays.

John Condeelis
Molecular basis of amoebiod chemotaxis.

Winfried Edelmann
Mouse models for colorectal cancers, tumor suppressor genes and DNA repair genes.

Thomas Graf
Stem cell plasticity; hematopoietic stem-cell biology: leukemo-genesis and transcription factors

Susan B. Horwitz
Mechanism of action and resistance to taxol.

Ganjam Kalpana
Molecular analysis of HIV-1 integration.

Jack Lenz
Retrovirus molecular genetics cancer, immuno-deficiencuy and human evolution.

Ari Melnick
Role of Chromatin remodeling and epigenetics in hematopoiesis and hematologic malignancies.

Tamar Michaeli
Signal transduction pathways regulating cellular proliferation differentiation and physiology

Jeffrey Pollard
Estrogen and progesterone regulation of uterine and mammary gland cell proliferation and differentiation, placental immunity.

Jeffrey E. Segall
Cell motility chemotaxis, matastasis of tumor cells.

Bridget Shafit-Zagardo
Molecular Neurobiology, developmental neurobiology.

David A. Shafritz
Liver-specific gene expression; hepatic stem cells; liver cell trsplantation and gene therapy.

Arthur I. Skoultchi
Control of cell proliferation and differentiation and leukemia.

E.R. Stanley
Growth factor and signal transduction in the regulation of cell proliferation and development.

Hilda Ye
Oncogenes in hematopoiesis.

Liang Zhu
Relinoblastoma protein family of growth suppressors and cell-cycle control.

Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics

 

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Cell Biology Jonathan M. Backer
Signaling by phosphoinositol kinases.

Nancy Carrasco
The molecular biology of the iodide transporter in health and cancer.

Maureen J. Charron
Glucose transporters biology, Glucagons receptor, Hormone action, Cellular proliferation.

John Condeelis
Molecular basis of amoebiod chemotaxis.

Ana Cuervo
Mechanisms regulating protein degradation in mammalian liver and their changes during aging.

Susan B. Horwitz
Mechanism of action and resistance to taxol.

Margaret Kielian
Virus-membrane fusion; virus assemly.

U. Thomas Meier
Nucleocyttoplasmic transport.

Tamar Michaeli
Signal transduction pathways regulating cellular proliferation differentiation and physiology

Gregory Prelich
Transcriptional regulatory mechanisms.

Philipp E. Scherer
Protein and vesicle trafficking events in insulin-sensitive tissues.

Carl Schildkraut
Replication of viral DNA, oncogenes, and immunoglobulin genes role of nuclear localization in gene expression.

Jeffrey E. Segall
Cell motility chemotaxis, matastasis of tumor cells.

Dennis Shields
Protein sorting and processing in the secretory pathway.

Robert H. Singer
Cellcular molecular biology, spatial organization of specific nucleic acid sequences.

Arthur I. Skoultchi
Gene expression; chromatin structure; terminal differentiation knock-out mice.

Erik Snapp
Cell biology of secretory protein folding, regulation, organization and dynamics of protein translocation.

Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics

Jonathan R. Warner
Gene analysis of ribosome synthesis in yeast; regulation of MRNA splicing.

Duncan W. Wilson
Assembly of herpes simplex virus envelop: protein trafficking and membrane biology.

Hilda Ye
Oncogenes in hematopoiesis.

 

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Biochemistry (Note: if you are especially interested in structural biology, NMR, X-ray crystallography etc. you might want to visit the site of our sister training program in Molecular Biophysics. Students can rotate freely between labs involved in either program.)

Anne Bresnick
The molecular mechanisms regulating cell motility and cell division.

Dmitry Fyodorov
Chromosome assembly and dynamics; biochemistry of ATP-dependent chromatin romodeling factors; Drodophila melanogaster.

Thomas Leyh
Enzymology of sulfate activation.

Umadas Maitra
Mechanism and regulation of translation initiation in eukaryotic cells.

Charles Query
Protein-RNA interactions; mechanism and regulation of pre-mRNA splicing in mammalian cells.

Ian M. Willis
Gene transcription, protein-nucleic acid interactions.

 

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Microbiology
and Immunology
Arturo Casadevall
Immune responses to C.neoformans.

Tanya Dragic
Mechanisms of Viral entry into target cells.

David Fidock
Genetic and physiological investigations into chloroquine resistance in the human Malaria parasite plasmodium falciparum.

William R. Jacobs
Molecular genetic analyses of pathogenic mycobacteria.

Ganjam V. Kalpana
Molecular analysis of HIV-1 integration..

Margaret Kielian
Virus-membrane fusion; virus assemly.

Kami Kim
Malaria Serine Proteinases

Jack Lenz
Retrovirus molecular genetics cancer, immuno-deficiencuy and human evolution.

Stanley G. Nathenson 
Structural basis for antigen presentation to T-cell receptor.

Vinayaka Prasad
Molecular determinants of polymerase processivity, fidelity and nucleotide analog sensitivity in Human Immunodeficiency Reverse Transcriptase. resistance.

Steven Porcelli
T-cell recognition of lipid and glycolipid antigens; mechanisms of antigen processing and presentation.

Matthew Scharff
Instability of immunoglobulin genes and monoclonal antibodies in fungal infections.

Duncan W. Wilson
Assembly of herpes simplex virus envelop: protein trafficking and membrane biology.

 

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Genetics Nicholas Baker
Growth and development of drosophila.

Geoffrey Childs
Functional genomics, mechanisms of lineage specification and tumor classification using microarrays.

Ales Cvekl
Gene regulation in ocular cells and tissues, functional genomics

Winfried Edelmann
Mouse models for colorectal cancers, tumor suppressor genes and DNA repair genes

Scott Emmons
Regulation of cell fates by Hox genes, neuron differentiation in C. elegnas.

John Greally
Integrative epigenomics research in human disease.

William R. Jacobs
Molecular genetic analyses of pathogenic mycobacteria.

Zaven Kaprielian
Axon guidance in the developing central nervous system.

Jack Lenz
Retrovirus molecular genetics cancer, immuno-deficiencuy and human evolution.

Bernice E. Morrow
Human molecular genetics.

Laurie Ozelius
Molecular Neurogenetic Studies of Movement Disorders.

Gregory Prelich
Transcriptional regulatory mechanisms.

Arthur I. Skoultchi
Gene expression; chromatin structure; terminal differentiation knock-out mice.

Jonathan R. Warner
Gene analysis of ribosome synthesis in yeast; regulation of MRNA splicing.

 

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Developmental
Biology
Nicholas Baker
Growth and development of drosophila.

Ales Cvekl
Gene regulation in ocular cells and tissues, functional genomics

Scott Emmons
Regulation of cell fates by Hox genes, neuron differentiation in C. elegnas.

Todd Evans
Regulation of hematopoiesis and cardiogenesis by embryonic signaling pathways and GATA transcription factors.

Thomas Graf
Stem cell plasticity; hematopoietic stem-cell biology: leukemo-genesis and transcription factors

Zaven Kaprielian
Axon guidance in the developing central nervous system.

Liang Zhu
Relinoblastoma protein family of growth suppressors and cell-cycle control.

 Pamela Stanley
Glycobiology, glycosyltransferase gene knockout mice; glycans in signal transduction and cancer.

Dr. P.Stanley is also the director of the Training Program in Cellular and Molecular Biology and Genetics



 

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