Nerlov, C., Querfurth, E., Kulessa, H., and Graf, T. (2000) GATA-1 interacts with the myeloid PU.1 transcription factor and represses PU.1 dependent transcription (2000), Blood, in press

Kelly, L.M., Englmeyer, U., Tillmanns, S., Lafon, I., and Sieweke, M, Graf, T. (2000). MafB induces myelomonocytic differentiation. EMBO J., in press

Kim, W.Y., Sieweke, M. Ogawa,E. Wee, J.H., Englmeier, U., Graf, T. and Ito, Y.
(1999). Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains. EMBO J. 18, 1609-1620

McNagny, K.M., Sieweke, M., Döderlein, G., Graf, T. and Nerlov, C. (1998).
Regulation of eosinophil-specific gene expression by a C/EBP-Ets-1 complex and
GATA-1. EMBO J. 17, 3669-3680

Nerlov, C., McNagny, K., Döderlein, G., Kowenz-Leutz, E. and Graf, T. (1998). Distinct C/EBP functions are required for eosinophil lineage commitment and maturation. Genes & Dev. 12, 2413-2423

Nerlov, C. and Graf, T. (1998). PU.1 induces myeloid commitment in multipotent hematopoietic progenitors. Genes & Dev. 12, 2403-2412

Sieweke, M.H., Tekotte, H. and Graf, T. (1997). Cooperative interaction of Ets-1 with USF-1 on the distal enhancer of the HIV-1 LTR. EMBO Journal, 17, 1728-1739.

McNagny, K.M., Pettersson, I., Rossi, F., Flamme, I., Shevchenko, A., Mann, M. and Graf, T. (1997). Thrombomucin, a Novel Cell Surface Protein that Defines Thrombocytes and Multipotent Hematopoietic Progenitors. Journal of Cell Biology, 138, 1395-1407.

Frampton, J., Ramqvist, T. and Graf,T. (1996). v-Myb of E26 leukemia virus up-regulates bcl-2 and suppresses apoptosis in myeloid cells. Genes & Dev.10, 2720-2731

Sieweke, M. H., Tekotte, H., Frampton, J. and Graf, T. (1996). MafB is a direct interaction partner of Ets-1 that represses Ets-1 transactivation of the transferrin receptor gene and inhibits erythroid differentiation. Cell 85, 49-60.

Rossi, F., McNagny, K.M., Smith, G., Frampton, J. and Graf, T. (1996).Lineage commitment of transformed hematopoietic progenitors is determined by the level of PKC activity, EMBO J.15, 1894-1901.

Frampton, J., McNagny, K., Sieweke, M., Philip, A., Smith, G. and Graf, T. (1995) v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors. EMBO J. 14: 2866-2875.

Kulessa, H., Frampton, J. and Graf, T. (1995) GATA-1 reprograms avian myelomonocytic cell lines into eosinophils, thromboblasts, and erythroblasts. Genes & Development 9: 1250-1262.

Kraut, N., Frampton, J., McNagny, K. and Graf, T. (1994) A functional Ets DNA-binding domain is required to maintain multipotency of hematopoietic progenitors transformed by Myb-Ets. Genes & Dev. 8: 33-44.

Graf, T., McNagny, K., Brady, G. and Frampton, J. (1992) Chicken "erythroid" cells transformed by the Gag-myb-ets encoding E26 leukemia virus are multipotent. Cell 70, 201-213.

Lim, F., Kraut, N., Frampton, J. and Graf, T. (1992) Intramolecular repression of c-Ets-1 DNA-binding is removed in the v-Ets oncoprotein. EMBO J. 11, 643-652.

Metz, T. and Graf, T. (1991) Fusion of the nuclear oncoproteins v-Myb and v-Ets is required for the leukemogenicity of E26 virus. Cell 66, 95-105.

Introna, M., Golay, J., Frampton, J., Nakano, T., Ness, S. A. and Graf, T. (1990) Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene. Cell 63, 1287-1297.

Golay, J., Introna, M., Graf, T. (1988). A single point mutation in the v-ets gene of the E26 avian leukemia virus affects both erythroid and myeloid cell transformation and promotes a lineage conversion from macrophages to promyelocytes. Cell 55, 1147-1158.

Beug, H., Blundell, P.A. and Graf, T. (1987) Reversibility of differentiation and proliferative capacity in avian myelomonocytic cells transformed by tsE26 leukemia virus. Genes & Development 1, 277-286.

Graf, T., v.Weizsäcker, F., Grieser, S., Coll, J., Stehelin, D., Patschinsky, T., Bister, K., Bechade, C., Calothy, G. and Leutz, A. (1986) V-mil induces autocrine growth and enhanced tumorigenicity in v-myc transformed avian macrophages. Cell 100, 357-364.

Adkins, B., Leutz, A. and Graf, T. (1984) Autocrine growth induced by src-related oncogenes in transformed chicken myeloid cells. Cell 39, 439-445.

Please click on links below

Graf, T. (2000). Transcription factors that induce the commitment of multipotent progenitors: lessons from the MEP system.
In: Hematopoiesis: A Developmental Approach, L.Zon editor.
Oxford University Press

Sieweke, M. and Graf, T. (1998). A party of transcription factors during blood cell differentiation. Curr Opin Genet Dev. 1998 8, 545-51

Graf, T. (1998). Leukemogenesis: Small differences in Myb have large effects. Current Biology, 8, R353-R358.

Graf, T. (1992) Leukemogenesis by fused transcriptional activators: the Myb-Ets model. Current Opinion in Oncology 4, Suppl. 19-21.

Graf, T. (1992) Myb: a transcriptional activator linking proliferation and differentiation in hematopoietic cells. Current Opinion in Genetics & Development 2, 249-255.

Graf, T. (1988). Leukemia as a multisep process: Studies with avian retroviruses containing two oncogenes. Leukemia 2, 127-131.