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Journal Club


November 15, 1999. Wenyu Wang

"Unfolding and Folding of Escherichia coli Chaperonin GroES is Expressed by a 3-State Model" by T. Higurashi et al. JMB 1999, 291, 703.

December 13, 1999. Tom Newman

"Structural Changes Linked to Proton Translocation by Subunit c of the ATP Synthase" by V. K. Rastogi et al. Nature, 1999, 402,  263.

March 6, 2000. Tom Newman
"Structural Changes in Bacteriorhodopsin During Ion Transport at 2 Angstrom Resolution." by H. Luecke et al. Science, Vol. 286, pp 255-260, 1999.

April 3, 2000. Raymond Huang
"Identification of the Major Ab1-42-Degrading Catabolic Pathway in Brain Parenchyma: Suppression Leads to Biochemical and Pathological Deposition" by N. Iwata et al. Nature Medicine, 2000, Vol. 6, pp 143-150.

May 15, 2000. Masha Spektor
"Intercellular Calcium Waves in HeLa Cells Expressing GFP-Labeled Connexin
43, 32, or 26" by K. Paemeleire et al. Molecular Biology of the Cell, Vol.
11, pp. 1815-1827, 2000.

October 16, 2000. Raymond Huang
"RNAi: Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals" by P. D. Zamore et al. Cell, Volume 101, pp 25-33, 2000. 

November 6, 2000. Shi Zhong
"Regulation of Protein Secretion Through Controlled Aggregation in the Endoplasmic Reticulum" by V. M. Rivera et al. Science, 2000, Vol. 287, pp 826-830.

November 29, 2000. Masha Spektor
"Cardioprotection From Ischemia by a Brief Exposure to Physiological Levels of Ethanol" by C.-H. Chen et al. PNAS, 1999, 96, 12784.

October 29, 2001, Shi Zhong
"A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis" by S. M. Srinivasula et al. Nature, 2001, volume 410, pp. 112-116

November 26, 2001, Hong Ji
"Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila" by J. S. Steffan et al., Nature, 200, volume 413, pp. 739-743

December 11, 2001, Feng Guo
"Antibody catalysis of the oxidation of water" by P. Wentworth, Jr. et al., Science, 2001, volume 293, pp 1806-1811.

November 25, 2002, Hong Ji
"A Ni-Fe-Cu Center in a Bifunctional Carbon Monoxide Dehydrogenase/Acetyl-CoA Synthase"
T. I. Doukov et al. Science, vol. 298, pp 567-572, 2002.

December 9, 2002, Feng Guo
"Targeted Pharmacological Depletion of Serum Amyloid P Component for Treatment of Human Amyloidosis" M. B. Pepys et al. Nature, vol. 417, pp 254-259, 2002.

January 6, 2003, Todd Haim
"Reverse Engineering of the Giant Muscle Protein Titin" H. Li et al. Nature, vol. 418, pp 998-1002, 2002.

February 3, 2003, Jodi Basner
"Reverse Engineering Gene Networks Using Singular Value Decomposition and Robust Regression"
M. K. S. Yeung et al. Proc. Natl. Acad. Sci. USA, vol. 99, pp 6163-6168, 2002.

March 17, 2003, Boris Heifets
"Excitable Spatio-Temporal Chaos in a Model of Glycolysis"
G. Baier et al. J. Phys. Chem. B, 2002, Vol 106, pp 3275-3282.

April 14, 2003, Eliah Aronoff-Spencer
"Integrated Genomic and Proteomic Analyses of a Systematically Perturbed Metabolic Network"
T. Ideker et al. Science, vol. 292, pp 929-934, 2001.

April 21, 2003, David Li
"Crystallographic and Spectroscopic Characterization of a Nonheme Fe(IV)=O Complex"
J.-U. Rohde et al. Science, vol. 299, pp 1037-1039, 2003.

April 21, 2003, Josh Mincer
"Resistance Proof, Folding-Inhibitor Drugs"
R. A. Broglia et al. Journal of Chemical Physics, Volume 118, pp 4754-4758, 2003.

October 20, 2003, Josh Mincer
"Resistance Proof, Folding-Inhibitor Drugs" by R. A. Broglia et al.,
Journal of Chemical Physics, Volume 118, pp 4754-4758, 2003.

November 17, 2003, David Li
"Ni-Zn-[Fe4-S4] and Ni-Ni-[Fe4-S4] Clusters in Closed and Open Alpha Subunits of Acetyl-CoA Synthase/Carbon Monoxide Dehydrogenase" by C. Darnault et al.
Nature Structural Biology, 2003, Volume 10, pp 271-279.

December 1, 2003, Ying-Hua Wang
"An Open Conformation of Mammalian Cytochrome P450 2B4 at 1.6-A Resolution"
by E. C. Scott et al.
Proceedings of the
National Academy of Science USA, 2003, volume 100, pp 13196-13201.

December 15, 2003, Todd Haim
"Comparative Modeling of the Latent Form of a Plant Catechol Oxidase Using a Molluskan Hemocyanin Structure" by C. Gerdemann et al,
Journal of Inorganic Biochemistry, 2002, volume 89, pp 155-158.

January 12, 2004, Jodi Basner
"Micromechanical Mapping of Live Cells by Multiple-Particle-Tracking Microrheology"
by Y. Tseng et al.
Biophysical Journal, 2002, volume 83, pp 3162-3176.

February 2, 2004, Boris Heifets
"Opioid Receptor Random Mutagenesis Reveals a Mechanism for G Protein-Coupled Receptor Activation" by F. M. Decaillot et al.
Nature Structural Biology, 2003, Volume 10, pp 629-636.

March 8, 2004, Eliah Aronoff-Spencer
"Genome-Wide RNAi Analysis of Growth and Viability in Drosophila Cells" by M. Boutros et al.
Science, 2003, volume 303, pp 832-835.

March 29, 2004, John Wilson
"Structure and Mechanism of the Lactose Permease of Escherichia coli" by J. Abramson et al.
Science, 2003, volume 301, pp 610-615.

August 9, 2004, Josh Mincer
"Thermal-Activated Protein Mobility and its Correlation with Catalysis in Thermophilic Alcohol Dehydrogenase" by Z.-X. Liang et al.
PNAS, 2004, volume 101, pp 9556-9561.

November 1, 2004, Jorge Durand
"Microscale Transport and Sorting by Kinesin Molecular Motors" by L. Jia et al.
Biomedical Microdevices, 2004, volume 6, pp 67-74.

November 15, 2004, John Wilson
"Microtubules continuously dictate distribution of actin filaments and positioning of cell cleavage in grasshopper spermatocytes" by G. B. Alsop and D. Zhang.
Journal of Cell Science, 2004, volume 117, pp 1591-1602.

December 6, 2004, David Liebelt
"The Principle of Temperature-Dependent Gating in Cold- and Heat-Sensitive TRP Channels" by T. Voets et al.
Nature, 2004, volume 430, pp 748-754.

January 10, 2005, Vito Mennella
"Divergent Signals and Cytoskeletal Assemblies Regulate Self-Organizing Polarity in Neutrophils" by J. Xu et al.
Cell, 2003, volume 114, pp 201-214.

January 31, 2005, Makiko Uchida
"Synthetic Mammalian Prions" by G. Legname et al.
Science, 2004, volume 305, pp 673-676.

February 7, 2005, Ron Rice
"Crystal Structure of an Oxygen-Binding Heme Domain Related to Soluble Guanylate Cyclases" by P. Pellicena et al.
Proceedings of the National Academy of Sciences USA, 2004, volume 101, pp 12854-12859.

March 7, 2005, Ben Samuelson-Jones
"Hemoxygenase-2 Is an Oxygen Sensor for a Calcium-Sensitive Potassium Channel" by S. E. J. Williams et al.
Science, 2004, volume 306, pp 2903-2907.

March 15, 2005, Vito Mennella
"Membrane Insertion of Anthrax Protective Antigen and Cytoplasmic Delivery of Lethal Factor Occur at Different Stages of the Endocytic Pathway" by L. Abrami et al.
Journal Cell Biology, 2004, volume 166, pp 645-651.

April 4, 2005, Jorge Durand
"A(beta) Immunotherapy Leads to Clearance of Early, But Not Late, Hyperphosphorylated Tau Aggregates via the Proteosome" by S. Oddo et al.
Neuron, 2004, volume 43, pp 321-332

April 25, 2005, David Liebelt
"Kinetochore-Driven Formation of Kinetochore Fibers Contributes to Spindle Assembly during Animal Mitosis" by H. Maiato et al.
Journal of Cell Biology, 2004, volume 167, pp. 831-840.

May 9, 2005, Makiko Uchida
"The First Cleavage of the Mouse Zygote Predicts the Blastocyst Axis" by B. Plusa et al. Nature, 2005, volume 434, pp. 391-395.

May 16, 2005, Nicole McKinnon
"Two Substrate-Targeting Sites in the Yersina Protein Tyrosine Phospatase Co-operate to Promote Bacterial Virulence" by M. I. Ivanov et al.
Molecular Microbiology, 2005, volume 55, pp. 1346-1356.

November 7, 2005, Eric Hayden
"A Force-Dependent State Controls the Coordination of Processive Myosin V" by T. J. Purcell et al. Proc. Natl. Acad. Sci. USA, 2005, Volume 102, pp 13873-13878.

November 21, 2005, Dongyan Tan
"The C2 Domain of PKCd Is a Phosphotyrosine Binding Domain" by C. H. Bene et al.
Cell, 2005, Volume 121, pp 271-280.

December 5, 2005, Paul Riegelhaupt
"The Role of Electrostatics in the Interaction of the Inhibitory Region of Troponin I with Troponin C" by D. A. Lindhout et al.
Biochemistry, 2005, Volume 44, 14750-14759.

December 19, 2005, Timothy Sonbuchner
"Targeting Malaria Virulence and Remodeling Proteins to the Host Erythrocyte" by M. Marti et al.
Science, 2004, Volume 306, pp 1930-1933.

 


 


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