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The Gene Therapy Core has been established to enrich and facilitate
the research effort of the College-wide scientific community.
Currently, the core generates and provides recombinant adenoviral
vectors for gene transfer into cultured cells and in vivo.
The core provides shuttle vectors into which investigators can
insert their promoters and coding regions of choice. The core then
generates, purifies, tests and delivers the recombinant viruses to the
investigator. There are several stock viruses expressing marker
genes. These can be expanded to the amounts needed for ex vivo or in
vivo gene transfer. The core can also expand recombinant adenoviruses
provided by investigators. For a detailed user fee schedule, contact
Dr. Xia Wang (ext. 3018) or Dr. J. Roy-Chowdhury (ext. 2265).
Investigators wanting to introduce adenovirus-based gene transfer
techniques to their laboratory can make an appointment with Dr. Roy-Chowdhury
for preliminary discussion.
For laboratories with some experience in
generating adenoviruses, the core can perform a part of the procedure.
The user fee will be only for the part performed by the core. By the end of this year, the
core is planning to
introduce a service for generating recombinant lentiviral vectors.
Please
call or write (E-mail
chowdhur@aecom.yu.edu) to Dr. Roy-Chowdhury to discuss your needs.
Location: Ullmann 525
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