EINSTEIN-MONTEFIORE INSTITUTE FOR CLINICAL & TRANSLATIONAL RESEARCH

Projects

The table below lists the current projects taking place at the Einstein CRC. To find out more about a study, please call 718-430-8800.

Investigator Study Title Disease Focus
Michael H. Alderman, MD Action to Control Cardiovascular Risk in Diabetes (ACCORD) Diabetes
Michael H. Alderman, MD A Clinical Trial of Renin Profiling in Selection of Initial Antihypertensive Drug Hyptertension
Karen Ballaban-Gil, MD Childhood Absence Epilepsy: Rx, PK-Pd and Pharmacogenetics Epilepsy
Nir Barzilai, MD Searching for Longevity Genes in the Historically Unique Jewish Ashkenazi Population Aging
Nir Barzilai, MD Markers for Exceptional Longevity in Offspring of Centenarians Aging
Peter Belamarich, MD Study of Celesevelam HCl Administered to Pediatric Patients with Heterozygous Familial Hypercholesterolemia on a Stable Dose of Statins or Treatment Naive to Lipid-Lowering Therapy Cholesterol
Steve Berk, MD Does Interferon Alter Methadone Metabolism in HIV Patients? HIV
Robin Briehl, MD Structure Interaction & Mechanism in Sickle Hemoglobin Sickle Cell Anemia
Michael Brownlee, MD The Glucosamine Pathway and Reactive Oxygen Species in the Pathogenesis of Diabetic Complications Diabetes
Robert Burk, MD Identification of Gene Susceptibility Loci in Women with Cervical Cancer Cervical Cancer
Cathy Chuang, MD Effect's of Coenzyme Q10 in Parkinson's Disease- Phase III Parkinson's Disease
Susan Coupey, MD Functional Ovarian Hyperandrogenism in Minority Adolescents Adolescent Gynocology
Jill P. Crandall, MD Markers and Mechanisms of Macrovascular Disease in IDDM Diabetes
Jill P. Crandall, MD Genotypes and Phenotypes for Exceptional Longevity Diabetes
Jill P. Crandall, MD Type 1 Diabetes Genetics Consortium Diabetes
Jill P. Crandall, MD Safety and Tolerability of Resveratrol in Older Adults Diabetes
Jill P. Crandall, MD Heart Risk in Older Adults with Diabetes (HeartROADS) Diabetes
Jill P. Crandall, MD Diabetes Prevention Program Outcomes Study Diabetes
Jill P. Crandall, MD Epidemiology of Diabetes Intervention and Complications (EDIC) Diabetes
Jill P. Crandall, MD DCCT/EDIC Family Genetic Study Diabetes
Jill P. Crandall, MD Targeting Inflammation Using Salsalate for Type 2 Diabetes Diabetes
Jill P. Crandall, MD Pilot Study of Resveratrol in Older Adults Diabetes
Gabriele De Vos, MD Immunotherapy in Reducing Asthma Morbidity in Young Children at High Risk for Developing Persistant Asthma Asthma
Teresa DiLorenzo, PhD Immunologic Determinants of Type-1 Diabetes Diabetes
Joan DiMartino-Nardi, MD Cardiovascular Biomarkers in Obese Minority Youth Heart Disease
Mary E. Fabry, PhD Detection of Hypoxia in Sickle Cell Anemia by Susceptibility Effects in MRI Sickle
Cell
Anemia
Marta Feldmesser, MD Phase 4, Open-Label Pilot Study to Evaluate the Combination of Voriconazole and Anidulafungin for the Treatment of Subjects with Proven or Probable Invasive Aspergillosis Who Are Intolerant of Polyene Treatment  Infections Diseases
Eugene Fine, MD A Pilot and Feasibility Study of a Low Carbohydrate Diet in Patients with Advanced Cancer Cancer
Ruth Freeman, MD EMPOWIR - Enhance the Metabolic Profile of Women with Insulin Resistance Diabetes
Ilan Gabriely, MD Mechanisms of Hypoglycemia Associated Autonomic Functions Hypoglycemia
Sheryl Haut, MD Study to Evaluate Carisbamate, Topiramate, and Levetiracetam in Subjects with Partial Onset Seizures Seizures
Sheryl Haut, MD The Impact of Seizures in the Elderly on Cognition, Anxiety, and Sleep Seizures
Sheryl Haut, MD Study of Rufinamide Given as Adjuncitive Therspy in Patients with Refractory Partial Seizures Seizures
Sheryl Haut, MD Study of Rufinamide Given as Adjunctive Therapy in Patients with Refractory Partial Seizures Seizures
Sheryl Haut, MD Epilepsy Phenome/Genome Project: A Phenotype/genotype Analysis of Epilepsy Epilepsy
Meredith A. Hawkins, MD Effect of Hyperglycemia Per Se on Hepatic Glucose Production Diabetes
Meredith A. Hawkins, MD Role of the Glucosamine (GlcN) Pathway in Nutrient-Induced Insulin Resistance in Humans Diabetes
Meredith A. Hawkins, MD Central Mechanisms that Regulate Glucose Metabolism in Humans Diabetes
Meredith A. Hawkins, MD A Double Blind Placebo Controlled Pharmacodynamic Study of the Effect of INCB013739 on Insulin Sensitivity in Obese, Type 2 Diabetic Subjects Diabetes
Meredith A. Hawkins, MD The Role of Acute Combined Peroxisome Proliferator-Activated Receptors (PPAR) Alpha and Gamma Stimulation on Insulin Action in Humans Diabetes
Meredith A Hawkins, MD Central Mechanisms that Regulate Glucose Metabolism in Humans Diabetes
Meredith A. Hawkins, MD Effect of Reservatrol on Age-Related Insulin Resistance and Inflammation in Humans Diabetes
Betsy Herold, MDand Marla Keller, MD Genital Herpes Virus Before & After Treatment if Cervicovaginal Fluid from Herpes-Infected Women Affects HIV in Vitro Herpes and HIV
Betsy Herold, MDand Marla Keller, MD Post-coital Anti-Viral Activity of Cervicovaginal Secretions Following Intravaginal Application of 0.5% PRO 2000/5 Gel (P)  Women's Health
Betsy Herold, MDand Marla Keller, MD Safety of Combination Microbicides in Herpes and HIV Herpes and HIV
Rhoda Hirsch, MD Conformational Changes in Normal and Mutant Hemoglobins Blood Disorders
Thomas Hostetter, MD  Sodium Bicarbonate Supplementation in Chronic Kidney Disease:  Evaluation of Efficacy, Safety, and Beneficial Effects Kidney Disease 
Andrea A. Howard, MD, MS  Effect of Hepatitis C Treatment on Glucose Metabolism Infectious Diseases and Diabetes
Andrea A. Howard, MD, MS  Impaired Glucose Metabolism in HIV-infected Drug Users Infectious Diseases and Diabetes
Andrea A. Howard, MD, MS A Pilot Study of the Effect of Hepatisi C Treatment on Glucose Metabolism Infectious Diseases and Diabetes
Norman Ilowite, MD Trial of Early Aggressive Therapy in Juvenile Idiopathic Arthritis Pediatric Arthritis
Norman Ilowite, MD  Randomized Placebo Phase Study of Rilonacept in the Treatment of System Juvenile Idiopathic Arthritis (RAPPORT) Pediatric Arthritis
Frederick Kaskel, MD, PhD Focal Segmental Glomerulosclerosis Clinical Trial Pediatric Kidney Disease
Frederick Kaskel, MD, PhD The Prospective Study of Kidney Disease in Children (CKid) Pediatric Kidney Disease
Frederick Kaskel, MD, PhD Novel Therapy for Resistant FSGS (FONT) Pediatric Kidney Disease
Marla Keller, MDandBetsy Herold, MD Effects of Repeated Applications of Tenofovir Gel on Mucosal Mediators of Immunity and Intrinsic Antimicrobial Activity of Cervicovaginal Secretions in Women at Low Risk for HIV-I Infection HIV Prevention
Marla Keller, MDandBetsy Herold, MD Safety of Acidform Lubricant in Women at Low Risk for HIV-1 Infection   HIV Prevention
Unab Khan, MBBS Systemic Inflammation and Early Atherogenesis in At-Risk Adolescents: A Study of Inner City, Minority Adolescents with Obesity and Asthma Pediatric Respiratory and Obesity
Richard Lipton , MD  Magnetic Resonance Spectroscopy Imaging of the Hippocampus in Subjects at High Risk for Dementia and in Control Subjects Dementia and Aging
Richard Lipton , MD  Einstein Aging Study Aging
Jane Little, MD Pulmonary Hypertension in Sickle Cell Disease Sickle Cell Anemia
Jane Little, MD Pulmonary Aterial Hypertension in Sickle Cell Disease Sickle Cell Anemia
Rebecca Madan, MD BK Virus and Cytomegalovirus interferon-y T-Cell Response in Adult Renal and Pediatric Solid Organ Transplant Recipients Infectious Complications
Arnold Melman, MD Biomarers UrogenitalComplications of Type 2 Diabetes Mellitus Diabetes
Bernice Morrow, PhD  Genetics of Hearing Impairment Pediatric Genetics
Bernice Morrow, PhD Chromosome Rearrangements and Genetic Disorders Pediatric Genetics
     
Yasmin Mossavar-Rahmani, PhD Nutrition and Physical Activity Assessment Study Nutrition
Jeffrey Pollard, PhD Effects of Modulation of the Endometrial Cell Cycle on Xenografted Human Endometrium Women's Health
John Reinus, MD A Randomized Study of Stopping Treatment at 24 Weeks or Continuing Treatment to 48 Weeks in Treatment-Naive Subjects with Genotype 1 Chronic Hepatitis C Who Achieve an Extended Rapid Viral Response (eRVR) While Receiving Telaprevir, Peginterferon Alfa2a (Pegasys) and Ribavirin (Copegus)  Chronic Hepatitis C
Jessica Rieder, MD Evaluation of the Bronx Nutrition and Fitness Initiative for Teens Adolescent Obesity
Jessica Rieder, MD Evaluation of an Individually-Tailored, Community-Based Comprehensive Weight-Loss Program for Overweight, Inner-City Minority Adolescents Adolescent Obesity
Yolanda Rivas, MD The Role of Homocysteine and Technetium-99m-Mebrofenin Scan in the Diagnosis of Non-Alcoholic Steatohepatitis in Children Pediatric Liver Disease
Yolanda Rivas, MD Multi-center, Double-blind Study to Evaluate the Safety, Efficacy, and Pharmacokinetics of the Human Anti-TNF Monoclonal Antibody Adalimumab in Pediatric Subjects with Moderate to Severe Crohn's Disease Crohn's Disease
Yolanda Rivas, MD D-Lactic Acid and Early Marker for Necrotizing Entercolitis Gastroenterology
Namita RoyChowdhury, PhD& Jayanta RoyChowdhury, MBBS Inherited Disorders of Hepatic Bilirubin Glucuronidation Liver Disease
Arye Rubinstein, MD Pharmacokinetic Study of NABI-IGIV 10% in Subjects with Primary Immune Deficiency Disorders (PIDD) Immunology
Nanette F. Santoro, MD The KRONOS Early Estrogen Prevention Study (KEEPS) Women's Health
Nanette F. Santoro, MD Effects of Hyperestrogenemia on the LH Surge Women's Health
Nanette F. Santoro, MD Establishment of Regular Ovulation in Normal Menarche Women's Health
Nanette Santoro, MD Reproductive Physiology of Ovarian Cancer: Association of Menstrual Blood Loss with Hyperestrogenemia and Effects of Estrogen on Endometrial Tissue Women's Health
Nanette Santoro, MD The Effect of Estrogen on Skin Rigidity and Wrinkles Women's Health
Nanette Santoro, MD Modulation of the Human Endometrial Cell Cycle by Selective Estrogen Receptor Modulators (SERMs) Women's Health
Nanette Santoro, MD Progesterone Action in the Uterus of Mice and Humans Women's Health
Rachel Saunders-Pullman, MD Estrogen in Normal and Abnormal Motor Control Neurology
Ellie Schoenbaum, MD The Natural History of Menopause in HIV Infected Drug Users: Diabetes and Lipids Substudy Women's Health and HIV
Harry Shamoon, MD Modulation of Hypoglycemic Counterregulatory Responses Diabetes
CJ Segal Isaacson, EdD The Einstein Bariatric Surgery Pilot Study Obesity
Shlomo Shinnar, MD, PhD Consequences of Prolonged Febrile Seizures in Childhood Pediatric Seizures
Richard Smith, MD Molecular Classification of Head and Neck Tumors Using cDNA Microarray Analysis to Detect Prognosis and Response to Therapy Oncology
Seth Sokol, MD The Effect of Vitamin D Repletion on Endothelial Function and Inflammation in Patients with Coronary Atherosclerosis Arterial Blood Vessels
Joseph A. Sparano, MD Pilot Trial of Radioiodine Therapy for Metastatic Breast Cancer Breast Cancer
Simon Spivack, MD Genetics of Lung Disease (Exhaled Breath DNA Mthylation in Lung Carcinogenesis) Lung Disease
Daniel T. Stein, MD Lipid Interactions on Insulin Sensitivity: Screening, Mixed Meals Tolerance Test Diabetes
 
Daniel T. Stein, MD Study 2: Effects of Elevated Exogenous and Antilipolytic Suppression of Endogenous FFA on Insulin and C-Peptide Kinetics in Normal Subjects Diabetes
Daniel T. Stein, MD Study 3: Effects of Dietary Fatty Acids on Insulin & C-Peptide Kinetics in Normal Subjects Diabetes
Daniel T. Stein, MD Study 5: Lipid Interactions in Insulin Secretion Regulation of Intramyocellular Lipid Metabolism Diabetes
Daniel T. Stein, MD Study 6: Mechanisms of Fat Induced Insulin Resistance Diabetes
Daniel T. Stein, MD Lipid Interactions on Insulin Sensitivity: The Role of Exercise and Diabetes on Muscle Lipid Metabolism Diabetes
Daniel T. Stein, MD Metabolic Impact of Low Carb. vs. Low Fat Weight Obesity
Daniel T. Stein, MD Effects of Dietary Fatty Acids on Insulin and C-peptide Kinetics in Subjects at Risk for Type 2 Diabetes Diabetes
Daniel T. Stein, MD Effects of Dietary Fatty Acids vs. Triglycerides on Insulin and C-peptide Kinetics in Normal Subjects Diabetes
 
Daniel T. Stein, MD Physiological Determinants of Glucose Intolerance in Menopausal Women Diabetes
Daniel T. Stein, MD K-ATP Channel Activity on Insulin Resistance Diabetes
Katalin Susztak, MD, PhD The Molecular Profile of Diabetic Kidney Disease Kidney and Diabetes
Han-Mou Tsai, MD ADAMTS13 Deficiency in TTP Hematology
Joe Verghese, MBBS Latent Mobility Abnormalities and Frailty Neurology
Elizabeth Walker The Improving Diabetes Outcomes In-Person Study Diabetes
Thomas K. Weber, MD Genetic Predisposition to Colorectal Cancer and the NY Metropolitan Familial Colorectal Cancer Registry Colorectal Cancer
Judith Wylie-Rosett, EdD Diabetes Dietary Study (DDS) Diabetes and Diet
Judith Wylie-Rosett, EdD Chinese American Cardiovascular Health Assessment Lifestyle
Ronald Zolty, MD Beta Adrenergic Receptor Polymorphisms in Heart Failure Cardiology 
Ronald Zolty, MD  Polymorphisms of the Beta 1- and Beta 2- Adrenergic Receptors Influence Survival in Patients Receiving Metoprolol Succinate XL after Acute Myocardial Infarction Cardiology
Ronald Zolty, MD  Plasma Serotonin Levels in Subjects with Chronic Heart Failure as Compared to Normal Controls Cardiology
Joel Zonszein, MD Bypass Angioplasty Revascular Ization Investigation in Type 2 Diabetes (BARI2D) Diabetes and Heart Disease
     

 

 

 

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