Components of the Grant Proposal

Scientific

Administrative

Issues, Problems, and Goals Title 
Specific Aims Abstract
Background and Significance Personnel
Preliminary Data Resources
Methods Budget
Appendices

Issues, Problems, and Goals

Issue or problem whose importance is either obvious or briefly stated

Long-term "global" objective of project

Specific Aims

About one page in length

Typically includes short conceptual narrative followed by well-defined objectives and/or criteria from which the rest of the project is derived and level of success is determined

Relationship with experimental plan should be clear; methodology can be introduced 

Presented in a readable, often outline, form so that readers can see the precise questions to be answered and the outcomes anticipated

Background & Significance

Helps the reviewer to understand the problem being addressed

Avoids jargon that only experts will appreciate

Shows your understanding of the important issues in the discipline

Presents knowledge gap to be addressed and shows the uniqueness of your approach

Reviews the relevant literature objectively

Preliminary Data

Shows that the project is realistic and feasible

Shows that your team can successfully do the proposed work now

Convinces the reviewers that your hypothesis should be tested

Methods

Presents a detailed plan of attack for each specific aim              

Should support costs proposed in the budget                       

Describes how you will evaluate success in achieving your aims   

Provides a flow chart of logic for each experiment's results and the subsequent steps in the research plan

Addresses sub-optimal methodologies and offers rationale for their use

Includes time table, often at end of section, to make organization apparent

Appendices

New Guidelines:
http://grants.nih.gov/grants/guide/notice-files/NOT-OD-07-018.html
 

May include

Publications:

Applicants may submit up to 3 of the following types of publications. Any exceptions will be noted in specific FOAs.

Other:

Surveys, questionnaires, data collection instruments, clinical protocols, and informed consent documents may be submitted in the Appendix as necessary.

Paper PHS398 applications only may include full-sized glossy photographs of material such as electron micrographs or gels in the Appendix; however, an image of each (may be reduced in size but readily legible) must also be included within the page limitations of the Research Plan.

The Title

Choose a title that:

Helps the funder choose the best reviewer

Most scientists can understand

Honestly presents the proposal

Might remain appropriate for future renewals
 

The Abstract

Is a summary of your entire proposal - written LAST

Should be understood by scientists outside your field

Will be the first thing read by primary reviewers and the only thing read by some voting members of the review committee

Will influence the way reviewers approach the rest of the proposal

Writing an Abstract

State the problem and the long-term goals

State the specific aims of the current project

Describe the methodologies proposed

State the significance of the work

Personnel

WHO proposes to do a project is just as important as WHAT is being proposed because a grant is an investment, not a contract.  Reviewers need to be convinced that the research team is capable.  Evidence for this includes:

Education and training

Scientific track-record

Specific expertise 

Appropriate percent effort committed

Use of consultants to fill gaps in staff expertise

Resources

Is your research space adequate?

Will necessary equipment be available?

What shared research facilities are available?

Remember: If you declare the availability of a resource here, don't ask for the money to buy it in the budget

The Budget

   = the costs associated with your planned activities

Parts of the Budget

Personnel

Consultants

Equipment

Supplies

Travel

Other Expenses-

   - Patients

   - Animals

   - Construction and  renovation

   - Publication costs

   - Equipment service contracts

   - Telephone, fax, email

To develop a budget you must know:

What costs are allowable (depends on funding agency)

The F& A (Facilities and Administration cost--also known as "indirect cost") rate that will be applied by your institution

What types of "re-budgeting" are permitted during the post-award period

Whether  "cost sharing" is required

Whether unwritten upper limits exist for projects like yours and/or investigators at your level

REMEMBER:

Include ALL costs associated with your project

Use a "Budget Justification" section to give a brief but clear rationale for all budget categories and most budget items

Request assistance from your departmental administrator and/or Grant Accounting when questions arise

Check for inconsistencies between the budget and other parts of the proposal